Does smoking have an impact on fusion rate in single-level anterior cervical discectomy and fusion with allograft and rigid plate fixation?

Brief review

이 논문은 단일분절에 전방경유 경추 절제 및 유합술(ACDF)를 시행한 환자들을 대상으로 흡연여부가 유합률에 영향을 주는가에 대해 연구한 내용 입니다.

단일 분절에 ACDF를 시행한 환자 573명(흡연자156명+비 흡연자417명)의 데이터를 분석하여 수술시점으로부터 2년이 지난 후, 방사선학적 측정을 통해 유합률을 조사하였습니다

.

결과적으로 본 연구의 대상이 된 흡연, 비 흡연 환자들 간의 유합률에는 통계적으로 유의한 차이가 없다고 합니다. (p=0.867)

*Title: Does smoking have an impact on fusion rate in single-level anterior cervical discectomy and fusion with allograft and rigid plate fixation?

흡연이 동종골과 금속판 고정을 동반한 전방경유 경추 절제 및 유합술에서 유합률에 영향을 미치는가?

*Authors: Myles Luszczyk, Justin S. Smith, Jeffrey S. Fischgrund, Steven C. Ludwig, Rick C. Sasso, Christop her I. Shaffrey, Alexander R. Vaccaro

*Bibliography: J Neurosurg Spine. 2013 Nov;19(5):527-31.

Object

Effect of smoking on fusion rates of the cervical and lumbar spine

: -In multilevel fusions: shown to negatively affect. (in cervical and lumbar)

-In single-level anterior cervical discectomy and fusion(ACDF): has yet to investigated.

Purpose: To address the effect of smoking on fusion rates in patients undergoing a 1-level ACDF with allograft and a locked anterior cervical plate.

Methods

▶Subject: patients underwent a 1-level ACDF with allograft and a locked cervical plate.

▶Subject number: 573 patients(156 smokers + 417 nonsmokers)

▶follow-up period: 24 months

▶Evaluation method: assessed radiographic evidence (lateral, neutral, and flexion/extension)

-The authors reviewed subject patients data.

Results

▶Overall fusion rate: 91.4% (all patients)

▶Solid fusion:

- nonsmokers: 382 patients (91.6%)

- smokers: 142 (91.0%)

-->No difference in the union rates between smokers and nonsmokers.(p=0.867)

Conclusions

Not significantly different in fusion status between smokers and nonsmokers who underwent a single-level ACDF with allograft and a locked anterior cervical plate.