레이블이 complications인 게시물을 표시합니다. 모든 게시물 표시
레이블이 complications인 게시물을 표시합니다. 모든 게시물 표시

2014년 10월 14일 화요일

합병증은 최소침습 척추수술의 초기 학습곡선과 연관성이 있다 Complications associated with the initial learning curve of minimally invasive spine surgery: a systematic review

Brief review

최소침습적인 척추수술의 Learning curve(학습곡선)을 주요 항목으로 하여 체계적 문헌고찰을 시행한 연구 입니다.
Pubmed에서 검색된 논문을 정해진 프로토콜대로 리뷰하여 최종적으로 15개의 논문이 선택되었습니다.
각 연구별로 complication, procedure time, fusion rate, estimated blood loss, level of evidence, sample size, intervention, study design등을 조사하여 정리하였습니다.
decompressive procedure에서는 durotomy, 그리고 fusion에서는 implant malposition,neural injury, and nonunion가 가장 흔한 합병증이라는 결과가 나왔습니다.
또 수술 후의 전체적인 합병증 발병률은 11%입니다.
아래 링크 따라가시면 전문 보실 수 있습니다^^


*Title: Complications associated with the initial learning curve of minimally invasive spine surgery: a systematic review
합병증은 최소침습 척추수술의 초기 학습곡선과 연관성이 있다: 체계적 문헌고찰

*Authors: Sclafani JA, Kim CW



BACKGROUND
-There is an inherently difficult learning curve associated with minimally invasive surgical (MIS) approaches to spinal decompression and fusion.
-The association between complication rate and the learning curve remains unclear.


QUESTIONS/PURPOSES
-Evaluated the learning curves of MIS procedures for the spine
-Defined as the change in frequency of complications and length of surgical time as case number increased, for five types of MIS for the spine.


METHODS
Searching protocol: PubMed database
-terms: "minimally invasive spine surgery AND complications AND learning curve”

Clinical outcome and learning curve metrics were categorized for analysis by surgical procedure (MIS lumbar decompression procedures, MIS transforaminal lumbar interbody fusion, percutaneous pedicle screw insertion, laparoscopic anterior lumbar interbody fusion, and MIS cervical procedures).

Procedure time and complication rate: the most consistent parameters to evaluate the learning curve

total 15 original studies are remained.

 

RESULTS
-The most common learning curve complication for decompressive procedures was durotomy.
-For fusion procedures, the most common complications were implant malposition, neural injury, and nonunion.
-The overall postoperative complication rate was 11% (109 of 966 cases).
-The learning curve was overcome for operative time and complications as a function of case numbers in 20 to 30 consecutive cases for most techniques discussed within this review.


CONCLUSIONS
-The quantitative assessment of the procedural learning curve for MIS techniques for the spine remains challenging because the MIS techniques have different learning curves and because they have not been assessed in a consistent manner across studies.

-Complication rates may be underestimated by the studies we identified because surgeons tend to select patients carefully during the early learning curve period.


-The field of MIS would benefit from a standardization of study design and collected parameters in future learning curve investigations.

2014년 1월 6일 월요일

Fusion risk score: evaluating baseline risk in thoracic and lumbar fusion surgery

Brief review

이 논문은 척추유합술의 위험도를 score로 나타내는 FRS(Fusion Risk Score)와 관련된 내용 입니다. 두 가지 만성질환이 동시에 나타나는 범위와 수술적 요소(접근방법, 레벨, 골절술) 등이 수술 위험도의 예후인자로서 증명되었다는 사실을 바탕으로  후향적 연구를 진행하였습니다. 
해당기간 내에 흉추 혹은 요추에 유합술을 시행한 364명의 환자를 대상으로 신장, 폐, 심장등에서의 만성질환과 나이, 당뇨병, approach방법, level등을 조사하였고 FRS scale로 나타냈습니다.
그 결과, 위의 항목들은수술에 대한 예후인자로서 통계적으로 유의한 값을 나타내었습니다. (p값이 모두 0.05보다 작았다)
FRS는 유합술을 받은 후의 위험성을 예측하며, FRS 를 환자에게 적절히 이용하면 외과의는 수술 전후의 위험성을 통제할 수 있다는 결론 입니다.


*Title: Fusion risk score: evaluating baseline risk in thoracic and lumbar fusion surgery.
유합술 위험도 지수: 흉추와 요추 유합술의 기준 위험치 평가

*Authors: Nathan L. Hartin, Amir A. Mehbod, Siddharth B. Joglekar, Ensor E. Transfeldt





STUDY DESIGN
Retrospective cohort study.



OBJECTIVE
Fusion Risk Score (FRS)
-To assess the risk of spine fusion surgery preoperatively.
-To control risk through tailoring intervention and explain differences in complication profile in high-complexity practice (for surgeon)



SUMMARY OF BACKGROUND DATA
-Research has identified and elevated risk of fusion surgery in elderly, yet the rate of such surgery continues to increase.
-A range of comorbidities and the surgical factors are demonstrated predictors of perioperative risk.



METHODS
Retrospective review
Subject number: 364 fusion patient (over 65yrs)
Follow-up period: 18-month
-Logistic regression analysis: To identify factors predictive for perioperative events.
-The predictive variables: incorporated into the FRS scaled from 1 to 20.
-Patient demographics and comorbidities: incorporated into the FRS patient score (maximum 10)
-surgical approach, levels, and osteotomies: FRS procedure score (maximum 10).



RESULTS
Multivariate analysis demonstrated those(1~8) are predictive of perioperative events.
1. chronic kidney disease (odds ratio [OR] = 5.3, 95% confidence interval [CI]: 1.5-18.6, P = 0.008),
2. chronic obstructive pulmonary disease (OR = 5.3, 95% CI: 2.0-14.2, P < 0.001),
3. ischemic heart disease (OR = 4.1, 95% CI: 2.0-8.4, P < 0.001)
4. open anterior approach (OR = 3.6, 95% CI: 1.4-9.3, P = 0.010)
5. diabetes (OR = 3.0, 95% CI: 1.4-6.4, P = 0.004)
6. previous spinal surgery at the same site (OR = 2.6, 95% CI: 1.3-4.9, P = 0.005)
7. age (OR = 1.07, 95% CI: 1.01-1.13, P = 0.019)
8. the number of motion segments fused (P = 0.049)

- FRS was highly predictive of 1)perioperative events, 2)intensive care unit admission, 3)operative time, 4)blood loss, 5)length of stay(all P < 0.0001).

-A score over threshold 9 carries a greater than 50% risk of perioperative events.

(처음에 연구대상 환자가 436명이었으나 동의서 받지 못한 환자, missing data, 연구제외기준에 해당하는 환자를 차례로 제외하고 나니 364명이 남았음)



CONCLUSION
-The FRS predicts the risk of complications after spine fusion surgery and risk of intensive care unit admission, operative time, blood loss, and postoperative length of stay.
-By balancing the FRS procedure score to the patient, the surgeon can quantify and control perioperative risk.



Odds ratio [OR]: 두 집단(실험군, 대조군)의 이항변수(성공, 발병 등)에 관한 승산 비를 나타내는 단위(배율)
예) 수술 성공 비, 질병 발병률 등.
이 논문의 result에 나온 내용을 예로 들어보면, 
choronic kidney disease(만성 신장 질환)의 Odds ratio (OR )=5.3 일 때
만성신장질환을 함께 가지고 있는 환자가 척추유합술을 시행했을 경우, 신장질환이 없는 환자에 비해 수술전후의 위험도가 5.3배 높다는 것 입니다.
odds ratio에 관한 자세한 내용은 빠른 시일 내에 정리하여 포스팅 하겠습니다.


2013년 11월 25일 월요일

Interspinous spacers compared with decompression or fusion for lumbar stenosis: complications and repeat operations in the medicare population

Brief review



*Title: Interspinous spacers compared with decompression or fusion for lumbar stenosis: complications and repeat operations in the medicare population.

*Author: Richard A. Deyo, Brook I. Martin, Alex Ching, Anna N. A. Tosteson, Jeffrey G. Jarvik, William Kreuter, Sohail K. Mirza.




STUDY DESIGN
Retrospective cohort analysis of Medicare claims for 2006-2009.


OBJECTIVE
To examine whether interspinous distraction procedures are 1)used selectively in patients with more advanced age or comorbidity.
2)associated with fewer complications, lower costs, and less revision surgery than laminectomy or fusion surgery.


SUMMARY OF BACKGROUND DATA
There are few population-based data evaluating patterns of interspinous spacer surgery and nonsurgical care.


METHODS
Medicare inpatient claims data divided into 4 groups. (with stenosis undergoing surgery, n = 99,084)
(1) interspinous process spacer alone
(2) laminectomy and a spacer
(3) decompression alone
(4) lumbar fusion (1-2 level)

-To compare age and comorbidity, cost of surgery, rates of revision surgery, major medical complications, wound complications, mortality, and 30-day readmission rates.


RESULTS
Age: received spacers > decompression or fusion
Comorbidity: received spacers > decompression or fusion
Complications (major medical): spacer alone < decompression or fusion surgery
Hospital payments: fusion procedures > spacer surgery > decompression alone
-These associations persisted in multivariate models adjusting for patient age, sex, comorbidity score, and previous hospitalization.


CONCLUSION

Interspinous distraction procedures fewer complications, higher rates of revision surgery to compared with decompression or fusion.

2013년 11월 4일 월요일

An Institutional Six-year Trend Analysis of the Neurological Outcome After Lateral Lumbar Interbody Fusion: A 6-Year Trend Analysis of a Single Institution.

Brief review


*Title: An Institutional Six-year Trend Analysis of the Neurological Outcome After Lateral Lumbar Interbody Fusion: A 6-Year Trend Analysis of a Single Institution.
측부요추체 유합술 후의 신경학적 결과의 6년간 기관 동향 분석: 단일 기관의 6년간의 동향 분석

*Author: Alexander Aichmair, Marios G. Lykissas, Federico P. Girardi, Andrew A. Sama, Darren R. Lebl, Fadi Taher, Frank P. Cammisa, and Alexander P. Hughes




STUDY DESIGN
Retrospective case series.


OBJECTIVE
To evaluate the proportional trend of neurological deficits after lateral lumbar interbody fusion (LLIF) at a single institution.


SUMMARY OF BACKGROUND DATA
Lumbar nerve roots are prone to iatrogenic damage during the transpsoas approach in LLIF, and postoperative neurological sequelae remain a major concern.


METHODS
Subject number: 451 patients (undergone LLIF)

Period: 2006.03~2012.04

-The electronic medical records and office notes were retrospectively reviewed.
(For reports on postoperative neurological deficits)


RESULTS
>>The number of included patients who underwent LLIF
(mean follow up period: 15.4±9.2 months)
-2006~2008: 47 patients (group A)
-2009~2010: 155 patients (group B)
-2011~2012: 91 patients (group C)


>>Indicate a decreasing proportional trend or postoperative sensory deficits (SDs), motor deficits (MDs), and anterior thigh pain (TP).
-SDs- immediate postoperative: statistically significant in decreasing proportion (P=0.018)
         - last follow-up: close to statistically significant in decreasing proportion (P=0.126)

-TP -immediate postoperative: close to statistically significant in decreasing proportion 
         (P = 0.098)
  -last follow-up: close to statistically significant in decreasing proportion (P = 0.136)


CONCLUSION
The present data indicate a decreasing proportional trend for SDs, MDs, anterior TP
(Institutional learning curve during a 6-year time period of performing LLIF)