2014년 8월 11일 월요일

2013 impact factor (2014년 8월 업데이트)

2014년 8월에 impact factor가 업데이트 되었습니다!
전체적으로 오른 것 같네요. 특히 neurosurgery는 3.031까지 올랐네요!
아래는 spine분야 주요 저널의 impact factor 입니다.







2014년 8월 5일 화요일

European Spine Journal 8월호 (Volume 23, Issue 8, August 2014)

이번에 나온 European Spine Journal 8월호 입니다. (Volume 23, Issue 8, August 2014)
일부만 가져왔으니 전체 보시려면 Eur Spine홈페이지로 들어가세요^^
이번호에만 basilar invagination치료에 대한 논문이 3개나 나왔네요!









Obesity is associated with reduced disc height in the lumbar spine but not at the lumbosacral junction: 비만도는 요천추부 접합부가 아닌 요추의 디스크 높이 감소와 연관성이 있다

Brief review

연구는 비만도가 요천추부 접합부가 아닌 요추의 디스크 높이 감소와 연관성이 있다는 주제의 cross-sectional study 입니다.

비만도와 디스크 높이, 요천추부의 요통간의 연관성을 보기 위하여 연구 대상자 72명의 MRI 흉추12(T12)~천추까지 촬영하여, 자료를 가지고 L1-L2~L5-S1 디스크 높이를 측정하였습니다. 또, 비만도(BMI) 측정하였고, 이전 2주간의 요통도 평가하였습니다.

결과적으로 전체 요추 디스크의 높이가 비만인 그룹이 비만이 아닌 그룹에 비해 감소되는 양상을 보였습니다. 특히 비만도는 L1-2 L3-L4에서 디스크 높이의 감소와 연관성을 보였고, 요천추부 접합부에서는 유의한 관련성이 없었습니다.
그리고 요추 디스크의 높이는 최근의 요통과는 유의한 연관성이 없었습니다.

비만도는 요추에서 디스크 높이의 감소와 연관성이 있지만, 요천추부 접합부에서는 관련이 없다는 결론 입니다. 초록이 너무 길다면 아래 키포인트만 보세요!

비만일수록 디스크 높이가 낮아지는 양상을 보인다면, 다양한 질환으로 이어질수도 있겠네요.. 비만은 만병의 근원!


*Title: Obesity is associated with reduced disc height in the lumbar spine but not at the lumbosacral junction
비만도는 요천추부 접합부가 아닌 요추의 디스크 높이 감소와 연관성이 있다.
*Authors: Urquhart DM, Kurniadi I, Triangto K, Wang Y, Wluka AE, OʼSullivan R, Jones G, Cicuttini FM


STUDY DESIGN
Cross-sectional, community-based study


OBJECTIVE
To investigate the relationships between obesity, disc height, and low back pain in the lumbosacral spine.


SUMMARY OF BACKGROUND DATA
Although obesity is a recognized risk factor for low back pain, our understanding of the mechanisms for this is limited.
The evidence for an association between obesity and spinal structural changes is also conflicting.


METHODS
-Seventy-two participants underwent magnetic resonance imaging from the T12 vertebral body to the sacrum. 
-Disc height was measured from L1-L2 to L5-S1.
-Body mass index(BMI) as measured and low back pain in the previous 2 weeks was assessed.


RESULTS

-연구 대상자들의 demographic data









































-요천추부에서 비만도와 디스크 높이의 연관성


-요추와 요천추부 디스크 높이와 최근 요통과의 연관성




-The mean and total lumbar disc heights were reduced in obese individuals compared with nonobese individuals.

-Although obesity was associated with reduced disc heights at the L1-L2 and L3-L4 levels, there were no significant relationship at the lumbosacral junction.

-Both mean and total lumbar disc heights were negatively associated with recent pain after adjusting for age, sex, and height.

-There were no significant relationships between disc height and recent pain at the lumbosacral junction.


CONCLUSION
-Obesity was associated with reduced disc height in the lumbar spine, but not at the lumbosacral junction, suggesting these joints may have different risk factors. 

-There was also evidence for an inter-relationship between obesity, lumbar disc height, and recent pain, suggesting that structural changes have a role in back pain and may in part explain the association between obesity and back pain.

2014년 7월 27일 일요일

우리들병원 이정환 원장 The Spine Journal논문 등재- Comparison of cervical kinematics between patients with cervical artificial disc replacement and anterior cervical discectomy and fusion for cervical disc herniation

Brief review
우리들병원 이정환 원장님이 The Spine Journal 최신호에 출판한 논문 입니다.

경추 디스크 탈출증이 있어 cervical artificial disc replacement혹은 anterior cervical discectomy and fusion을 받은 환자들을 대상으로 경추의 운동학적인 결과를 비교한 연구입니다.
임상적 결과로서 통증지수(VAS), 일상생활 장애지수(K-NDI)를 측정하였고, 운동학적인 결과분석을 위해 3차원 동작분석을 시행했습니다.

측정결과, VAS, NDI등의 임상결과는 두 군간에 유의한 차이가 없었습니다.
3D 동작분석 결과, cervical artificial disc replacement를 받은 환자군이 anterior cervical discectomy and fusion를 받은 환자군에 비해 굽힘, 편 상태에서 움직임의 범위가 통계적으로 유의하게 유지되었습니다.
아래 링크 들어가서 읽어보세요^^



*Title: Comparison of cervical kinematics between patients with cervical artificial disc replacement and anterior cervical discectomy and fusion for cervical disc herniation.


*Authors: Lee JH, Kim JS, Lee JH, Chung ER, Shim CS, Lee SH




BACKGROUND CONTEXT
Although anterior cervical discectomy and fusion (ACDF) is an effective treatment option for patients with cervical disc herniation, it limits cervical range of motion, which sometimes causes discomfort and leads to biomechanical stress at neighboring segments.

In contrast, cervical artificial disc replacement (ADR) is supposed to preserve normal cervical range of motion than ACDF. A biomechanical measurement is necessary to identify the advantages and clinical implications of ADR.

However, literature is scarce about this topic and in those available studies, authors used the static radiological method, which cannot identify three-dimensional(3-D) motion and coupled movement during motion of one axis.


PURPOSE
-To compare the clinical parameters and cervical motion between ACDF and ADR (by 3-D motion analysis)
-To investigate the ability of ADR to maintain cervical kinematics.


STUDY DESIGN
Prospective case control study.


PATIENT SAMPLE
Patients who underwent ADR or ACDF for the treatment of single-level cervical disc herniation.


OUTCOME MEASURES
Visual analog scale (VAS)
Korean version of Neck Disability Index (NDI, %)
3-D motion analysis


METHODS
-Clinical outcomes: evaluated by VAS and the Korean version of the NDI (%) to assess pain degree and functional status.

-Cervical motions: assessed by 3-D motion analysis in terms of sagittal, coronal, and horizontal planes.
(Markers of 2.5 cm in diameter were attached at frontal polar (Fpz), center (Cz), and occipital (Oz) of 10-20 system of electroencephalography, C7 spinous process, and both acromions)

-These evaluations were performed preoperatively and 1 month and 6 months after surgery.





RESULTS
»Pre op: no significant difference in VAS, NDI (%), and cervical range of motion (between two groups)

»After surgery:
-no significant difference in VAS and NDI (%)

-In motion analysis, significantly more range of motion was retained in flexion and extension in the ADR group than the ACDF group at 1 month and 6 months.

There was no significant difference in lateral tilt and rotation angle. In terms of coupled motion, ADR group exhibited significantly more preserved sagittal plane motion during right and left rotation and also showed significantly more preserved right lateral bending angle during right rotation than ACDF group at 1 month and 6 months. There was no significant difference in other coupled motions.
 



CONCLUSION
-3-D motion analysis could provide useful information in an objective and quantitative way about cervical motion after surgery. In addition, it allowed us to measure not only main motion but also coupled motion in three planes.

-ADR demonstrated better retained cervical motion mainly in sagittal plane (flexion and extension) and better preserved coupled sagittal and coronal motion during transverse plane motion than ACDF.

-ADR had the advantage in that it had the ability to preserve more cervical motions after surgery than ACDF.

2014년 7월 17일 목요일

The Spine Journal 7월호 논문 목록

The Spine Journal에서 나온 7월호 논문 목록 입니다.
일부만 가져왔으니 나머지는 저널 홈페이지에서 보시면 됩니다^^ (이레 링크 참조)







2014년 7월 16일 수요일

Stand-Alone Anterior Lumbar Interbody Fusion for Degenerative Disc Disease of the Lumbar Spine: Results With a Two Year Follow Up

Brief review

SPINE지의 최신호에 나온 논문 입니다.
퇴행성 디스크 질환이 있는 환자들에게 stand alone 전방경유요추체간 유합술을 시행한 후 2년이 지난 후의 임상적, 방사선학적 결과를 관찰한 연구 입니다.
허리,다리의 통증지수(VAS) 및 일상생활장애지수(ODI) 가 수술전에 비해 유의하게 감소하였고, 인접분절의 disc height도 감소되지 않는 좋은 결과가 나왔네요.
아래의 링크로 들어가서 한번 읽어보세요^^ 시간 없으시면 아래의 key points만 읽어봐도 도움이 될 듯 합니다.

*Title: Stand-Alone Anterior Lumbar Interbody Fusion for Degenerative Disc Disease of the Lumbar Spine: Results With a Two Year Follow Up.
*Authors: Lammli J, Whitaker C, Moskowitz A, Duong J, Dong F, Felts L, Konye G, Ablah E, Wooley P.
*Bibliography: Spine (Phila Pa 1976). 2014 May 12. [Epub ahead of print]

Study Design
Retrospective chart review

Objective
To report outcomes of a consecutive series of patients diagnosed with degenerative disc disease (DDD) between L4 and S1, treated with stand alone Anterior Lumbar Interbody Fusion (ALIF, either one or two-level) and use of rhBMP-2 for bony fusion with instrumented fixation.

Summary of Background Data
Degeneration of the lumbar spine is described as lumbar spondylosis, or DDD. To treat DDD, surgical interventions include: ALIF, circumferential fusion (360° fusion), posterior spinal fusion (PSF), and total disc replacement (TDR). Currently, there has been paucity in the literature on the evaluation of ALIFs.

Methods
Researchers reviewed a consecutive series of patients with DDD that had undergone a 1-level or 2-level ALIF between 2005 and 2010, with the use of rhBMP-2. Patients' clinical and functional outcomes were documented. Radiographs were analyzed for disc height, mean optical density, and integrated optical density. Operative time, length of hospital stay, and estimated blood loss were also reported.



























Results
Patients' two year Oswestry Disability Index (ODI) and Visual Analog Scale (VAS) scores significantly improved from pre-surgery (p ≤ 0.0001). Patients' two year post-operative disc height was significantly greater than the pre-operative disc height at the fused level (p ≤ 0.0001); there was no significant difference at the level adjacent to fusion. Majority of patients (107 of 115, 93.0%) satisfied fusion criteria based on mean optical density. Intra-operative time, estimated blood loss, and hospital stay was significantly fewer with 1-level and 2-level ALIFs than 360 fusions and TDR.




















Conclusion

Stand alone ALIF used to treat DDD can produce comparative clinical and functional outcomes. ALIFs showed significant decreases in blood loss, operative time, and hospital stay. Furthermore, at two years' time, mean optical density suggests high rate of bony fusion, and no significant loss of disc height was noted at the adjacent level.


2014년 7월 6일 일요일